Roaccutane protocol
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Roaccutane protocol

bulletBefore you leave the rooms
bulletYour blood test results
bulletHow to fill your diary
bulletOne month visit
bulletSubsequent monthly visits
bulletMore about blood tests
bulletWhat tests are taken
bulletHow long will treatment be administered for
bulletHow to calculate your dosage and duration of treatment
bulletWhat happens if the acne flares up (worsens)

For frequently asked questions on Roaccutane, click here.

If you are about to commence or have just been commenced on Roaccutane, read on.

Before you leave the rooms

bulletCollect the following documents from the secretary on your way out:

Your blood test form 
An information booklet on Roaccutane
Roaccutane Diary
The practice web address so that you could read the FAQ page on Roaccutane in our web site.

bulletAll female patients to read and sign consent form and to have a negative pregnancy test before collecting script for Roaccutane
bulletMake your follow-up appointment for one month.
bulletGo to the path lab to have your blood test taken.
bulletIf you are taking your blood tests later (not on the same day as your consultation), it is preferable to take it fasting ie. eat nothing from 10pm the previous night and take the test in the morning.
bulletIf you belong to a medical aid which allows you to obtain Roaccutane as a "chronic medication", bring in the forms for completion, along with your prescription.  The medical aid takes about two weeks to authorise Roaccutane on such a plan.  Cost of filling Chronic Medication plan forms is R60-00.
bulletThe medical aid sometimes requires a letter of motivation.  The cost of writing this letter is R60-00.  Add R20-00 for one photograph and R40 for two.
bulletPhone the rooms (265 1505) after one week for your test results and to find out if you can start Roaccutane.  Please note that results are not phoned through to patients, even if the results are abnormal.
bulletIf the test results are normal, you will be advised accordingly by the secretary.  You may then start the Roaccutane.
bulletIf the results are abnormal, your call will be put through to doctor who will  discuss the results with you and advise you about the steps that are necessary to be taken subsequently.

How to fill in your diary

bulletWrite you name and personal particulars requested
bulletWrite the names of the months in the spaces provided
bulletFill in your weight.
bulletInsert one tick for each capsule taken.
bulletIndicate the start of each new box (N)
bulletIndicate the date of blood tests (B)
bulletIndicate the date of your visits (V)

Some of the information, eg side effects etc. may be recorded on the reverse of the page.

At each visit, the following will be checked.

bullet    Starting date of Roaccutane
bullet    Number of boxes completed (20mg x 60)
bullet    Number of months completed
bullet    Total number of capsules taken to date
bullet    Side effects 
bulletPlease bring your diary along at each visit.
bulletYou will need to mention the above details on your follow-up visit.

Follow up visits

bulletDuring you follow-up visit in one month, a clinical assessment will be made of your acne, side effects will be enquired about and ways of dealing with them will be discussed.  Your diary will also be checked.
bulletIf all is well, you will be called back once a month until the end of your treatment. 
bulletHowever, if you have any problems in between, you may phone in or send an e-mail, or make a booking to come in personally.

How long will treatment be administered for?

bulletRoaccutane is discontinued once a total dose of 120-150mg/kg is reached.  The total dose is calculated during your follow up visits.  The length of time that Roaccutane is taken varies between individuals.  On average, the duration of treatment is 4 to 6 months.

How to calculate your dosage and duration of treatment

Each box of Roaccutane contains 60 capsules (each capsule being 20mg).

weight in kg

dosage

no. of boxes

duration of treatment in months

upto 40  1 capsule twice a day 4 4
41-50 1 capsule twice a day 5 5
51-60 1 capsule twice a day 6 6
61-70 1 capsule twice a day 7 7
71-80 1 capsule twice a day 8 8
81-90 1 capsule twice a day 9 9
1 capsule three times a day 9 6
91-100 1 capsule twice a day 10 10
2 capsules twice a day 10 5

The starting dose varies around 0,5 mg per kg and can be stepped up depending on how well the medication is tolerated.

More about blood tests

bulletBlood tests are usually requested at the start of treatment, after one month and at the end of treatment.  However, additional tests may be requested between these times, depending of the results and response to treatment. 
bulletIf the second blood test is not entirely normal, you may need to have blood tests performed monthly and the dosage of Roaccutane may need to be adjusted.
bulletIf the blood test is completely abnormal, you may be asked not to start the Roaccutane.  In this case, an alternative medication may need to be chosen.

What tests are taken

bulletTests taken include:  AST, ALT, Bilirubin, Triglycerides and Cholesterol.  These tests are best taken fasting (no eating or drinking from 10pm the previous night).  However, if it is not convenient to take the bloods fasting, they  may be taken at any time, provided you realise that they may need to be repeated fasting if abnormal.

What happens if the acne worsens?

Take 10mg Prednisone (2 x 5mg tablets) daily for two weeks.  If the acne settles, stop the Prednisone.  If not, continue for a further two weeks.

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For frequently asked questions on Roaccutane, click here.

 
© Dr N Raboobee 2008
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